SNAP annotations: PDB entry 7jz0

PDB-id

7jz0; DSSR-derived features in text and JSON formats; DNAproDB

Class

viral protein-RNA

Method

X-ray (2.15 Å)

Summary

Crystal structure of sars-cov-2 nsp16-10 heterodimer in complex with (m7gpppa2m)pupupapapa (cap-1) and s-adenosyl-l-homocysteine (sah).

Reference

Minasov G, Rosas-Lemus M, Shuvalova L, Inniss NL, Brunzelle JS, Daczkowski CM, Hoover P, Mesecar AD, Satchell KJF (2021): "Mn2+ coordinates Cap-0-RNA to align substrates for efficient 2'-O-methyl transfer by SARS-CoV-2 nsp16." Biorxiv. doi: 10.1101/2021.01.31.429023.

Abstract