Summary information and primary citation
- PDB-id
-
1cgm;
DSSR-derived features in text and
JSON formats; DNAproDB
- Class
- virus
- Method
- fiber diffraction
- Summary
- Structure determination of cucumber green mottle mosaic
virus by x-ray fiber diffraction. significance for the
evolution of tobamoviruses
- Reference
-
Wang H, Stubbs G (1994): "Structure
determination of cucumber green mottle mosaic virus by
X-ray fiber diffraction. Significance for the evolution
of tobamoviruses." J.Mol.Biol.,
239, 371-384. doi: 10.1006/jmbi.1994.1379.
- Abstract
- Cucumber green mottle mosaic virus (CGMMV) is a
rod-shaped virus of the tobacco mosaic virus (TMV) group.
The structure of cucumber green mottle mosaic virus has
been determined by fiber diffraction methods at 3.4 A
resolution, and refined by molecular dynamics methods to an
R factor of 0.093. Disassembly of TMV is driven by the
mutual repulsion of intersubunit carboxyl-carboxylate
pairs, but one of these pairs is not conserved in CGMMV. An
alternative pair, located about 5 A from the site of the
TMV pair, has been found in CGMMV. Comparison of the two
structures suggests that the carboxylate groups are free to
migrate in the subunit interfaces during evolution.
