SNAP annotations: PDB entry 12sn

PDB-id

12sn; DSSR-derived features in text and JSON formats; DNAproDB

Class

viral protein-DNA

Method

cryo-EM (3.38 Å)

Summary

Sars-cov-2 RNA-dependent RNA polymerase in complex with 4'-fla nucleotide analogue

Reference

Walker SM, Loutan AJ, Tchesnokov EP, Kocincova D, Gordon CJ, Escobedo RA, Jackson N, Vogel OA, Morsheimer K, Park S, Gharpure A, Urbano I, Heacock M, Cheng Z, Pathak K, Wolff KC, Huerta L, Bakowski MA, Riva L, Gupta AK, Yu C, Das K, Martinez-Sobrido L, Basler CF, Davey R, Wilson IA, Ward AB, Chanda S, Chatterjee AK, Gotte M (2026): "Substrate and target selectivity of 4'-fluoroadenosine against viral and host polymerases." Biorxiv. doi: 10.64898/2026.05.22.727251.

Abstract