SNAP annotations: PDB entry 11gk

PDB-id

11gk; DSSR-derived features in text and JSON formats; DNAproDB

Class

RNA binding protein-RNA

Method

cryo-EM (3.0 Å)

Summary

Human argonaute2 r315v-h316a - guide RNA in complex with a fully complementary target (conformation 2)

Reference

Sarkar S, Gebert LFR, MacRae IJ (2026): "Catalytic activation of human Argonaute 2 requires RNA duplex deformation." Nat.Struct.Mol.Biol. doi: 10.1038/s41594-026-01840-5.

Abstract